anti-CD66b (ANC3C5) Biotinylated

INFORMATION: Human CD66b (CEACAM8, CGMb, NCA-95) is a 95kD member of the Carcinoembryonic Antigen (CEA) group. It is expressed on granulocytes and functions as an adhesion molecule.  Similar to the CD66 a, c, and d isoforms, engagement of CD66b on neutrophils causes increased adhesion to endothelial cells (2).  Crosslinking CD66b on neutrophils with antibodies triggers IL-8 release (3).

References:

1) W.N. Khan, S. Hammarstrom, et al. (1992) Genomics 14(2):384-90.

2) K.M. Skubitz, A.P. Skubitz, et al. (1996) J Leuk Biol 60(1): 106-117.

3) A.K. Schroder, L Rink, et al. (2006) Human Immunol 67(9): 676-682.

Antibody from clone ANC3C5 binds to CD66b on the cell surface of human PMN in Flow cytometry and works as an EIA capture or detection reagent for recombinant CD66b when paired with clone ANC4A4(Cat #220-020).

USD $325.00
In cart: 0
= $325.00
Catalog #:
219-030
Form:
Biotin
Size:
100 µg
Alternate Name:
CEACAM8, CGMb, NCA-95
Clone:
ANC3C5
Applications:
EIA, FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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