anti-CD60b Biotinylated

Human CD60 antigen is a glycolipid determinant found on about 30% of peripheral blood T cells.  The glycolipid determinant is linked to a glycoprotein which can transduce activation signals (1, 2).

Isotype: Murine IgM

Immunogen: Human rheumatoid synovial T cell line (ST-1)

Specificity: Antibody UM4D4 recognizes a 9-0-acetylated disialosyl group linked to the glycoprotein CD60b (1, 5,7).

Functional Application: Antibody UM4D4 will activate T cells.

References:

1. J.B. Higgs, et al, (1988) J Immunol  140: 3758-3765.

2.  D.A. Fox, et al, (1990) Cell Immunol  128: 480-489.

3.  B. Kniep, et al, (1993) Blood  82: 1776-1786.

4.  E.P. Rieber & G. Rank, (1994) J Exp Med  179: 1385-1390.

5.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 398-404.

7.  Mason, D., et al. 2002. Leucocyte typing VII. Oxford University Press, New York

8. Anna-Maria T Bauman, Martina Muhlenhoff, et al. (2015) Nature Communications 6: 7673. PMID: 26169044

USD $325.00
In cart: 0
= $325.00
Catalog #:
212-030
Form:
Biotin
Size:
100 µg
Clone:
UM4D4
Applications:
FC, FX, WB

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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