anti-CD59 Biotinylated

Human CD59 is a GPI anchored molecule that protects cells from complement-mediated lysis (1).  Studies are progressing to determine the regulatory mechanism for CD59 expression (2). A CD59-like protein has been discovered on the causative agent of Amebic encephalitis (3)

Isotype: Murine IgG1 kappa

Immunogen: Human K562 tumor cells

Specificity: Antibody BRA-10G reacts with the 18-22 kd CD59 molecule. It is useful in Flow cytometry, Western Blot(3)  and Immunoprecipitation(4).

References:

1)  Leukocyte Typing V (S F Schlossman, et al, eds.)  Oxford University Press, Oxford  (1995) p. 1476-1477.

2)  M H Holguin, et al, (1996) J Immunol 157: 1659-1668.

3) A E Fritzinger, F. Marciano-Cabral, et al. (2006) Infection and Immunity 74(2):1189-1195.

4) J Zhang, C Gerhardinger, M Lorenzi (2002) Diabetes 51(12): 3499-3504

5)  Barber, K.E., Ghebrehiwet, B., Yin, W. et al. (2017) Cel. Mol. Bioeng. 10: 124. 

USD $235.00
In cart: 0
= $235.00
Catalog #:
211-030
Form:
Biotin
Size:
100 µg
Alternate Name:
Protectin, MAC-inhibitor, MAC-IP
Clone:
BRA-10G
Applications:
EIA(5), FC, IP(4), WB(3)

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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