anti-CD45 FITC Conjugate

Human CD45 is expressed on all cells of hematopoietic origin, except erythrocytes.  CD45 is a transmembrane tyrosine phosphatase which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments.  CD45 plays an essential role in lymphocyte activation (2).

Isotype: Murine IgG2a kappa

Immunogen: Peripheral blood mononuclear cells

Specificity: Antibody C11 recognizes all isoforms of CD45.

References:

1.  U. Dianzani, et al, (1992) Eur J Immunol  22: 365-371.

2.  I.S. Trowbridge & M.L. Thomas, (1994) Annu Rev Immunol  12: 85-116.

3.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 386-399.

4.  D. Leitenberg, et al, (1996) J Exp Med  183: 249-259.

5.  M Vigano,  de Girolamo, et al. (Feb 2017) J Exp Orthopaedics 4: 8.

USD $210.00
In cart: 0
= $210.00
Catalog #:
196-040
Form:
FITC
Size:
120 tests
Alternate Name:
LCA, B220
Clone:
C11
Applications:
FC(5)

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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