anti-CD43 Biotinylated

Human CD43 is a heavily O-glycosylated and sialylated transmembrane protein that is mainly found on T cells, but not on B cells.

Isotype: Murine IgG1

Immunogen: Human KG-1 tumor cells

Specificity: Antibody DFT1 recognizes epitope A of the CD43 molecule on pMN of about 135 kd (1,3).

Functional Application: Antibody DFT1 partially induces apoptosis in hemopoetic progenitor cells and also induces hemopoetic aggregation.

References:

1.  W.P. Stross, et al, (1989) J Clin Pathol  42:953-961.

2.  Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989)  p. 1697-1713.

3.  Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 494-497.

4.  Pace K E, L G Baum, et al.  (1999) J Immunol 163(7): 3801 – 3811.