anti-CD34 Purified (with Antibiotics)

Human CD34 is an unusual glycosylated membrane protein exclusively expressed on immature hematopoietic cells and on endothelial cells.  CD34 may have a role in cell adhesion.  CD34 has extensive utility for bone marrow transplantation (3, 4).

Isotype: Murine IgG3 kappa

Immunogen: Human KG-1a tumor cells

Specificity: Antibody 43A1 recognizes the class II epitope of the 110 kd CD34 molecule (1, 2,) which is resistant to neuraminidase and sensitive to glycoprotease (6). 

References:

1.  H.J. Bühring, et al, (1991) Leukemia  5: 854-860.

2.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 840-874.

3.  R.H. Collins, (1994) Stem Cells  12: 577-585.

4.  T.L. Holyoake & M.J. Alcorn, (1994) Blood Reviews  8: 113-124.

5. J.P. Levesque, L.J. Bendell, et al. (2003) J Clin Invest 110: 187-196.

6.  Lanza R, Sutherland DR, et al. (2001) J Biol Regulators and Homeostatic Agents 15:1-13.

7.  M Vigano,  de Girolamo, et al. (Feb 2017) J Exp Orthopaedics 4: 8.  PMID: 28244027

8. Liang, Jf., Wang, Hk., Xiao, H. et al. (2010) J Exp Clin Cancer Res 29, 71. https://doi.org/10.1186/1756-9966-29-71.

USD $210.00
In cart: 0
= $210.00
Catalog #:
183-020
Form:
Pur/WA
Size:
100 µg
Clone:
43A1
Applications:
FC(7), FPS(8), WB

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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