anti-CD14 R-PE Conjugate

Human CD14 is strongly expressed on myelomonocyte lineage cells including monocytes, macrophages, and a subset of granulocytes.  CD14 is a high affinity receptor for complexes of lipopolysaccharide and lipopolysaccharide binding protein.  A soluble form of CD14 also binds to LPS and LBP (5). 

Isotype: Murine IgG2a

Immunogen: Human thymocytes/Sezary T cells

Specificity: Antibody UCHM1 recognizes an extracellular epiotpe of the human CD14 molecule of about 53 kd.  UCHM1 will also  immunoprecipitate a soluble form of CD14 (1, 2, 3).  It is crossreactive with cynomolgus monkey CD14 (6).

References:

1.  N. Hogg, et al, (1984) Immunology  53: 753-767.

2.  M.O. Labeta, et al, (1993) Eur J Immunol  23: 2144-2151.

3.  Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989)”Reference Antibody”.

4.  Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995)  p. 778-788.

5.  S.D. Wright, (1995) J Immunol  155: 6-8.

6. Yoshino N, Honda M, et al. (2000) Exp Anim 49(2):97-110.

USD $275.00
In cart: 0
= $275.00
Catalog #:
163-050
Form:
R-PE
Size:
120 tests
Alternate Name:
LPS-R
Clone:
UCHM1
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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