anti-CD13 R-PE Conjugate
Human CD13 is a zinc-binding aminopeptidase-N enzyme expressed on the surface of myeloid cells (2). IL-4 will upregulate expression of CD13 which may play an anti-inflammatory role (3).
Isotype: Murine IgG2a kappa
Immunogen: Human osteosarcoma tissue
Specificity: Antibody 22A5 recognizes the human cell surface aminopeptidase-N enzyme (1).
References:
1. M.A. Horton, et al, (1985) Cancer Res 45: 5663-5669.
2. R.A. Ashmun & A.T. Look, (1990) Blood 75: 462-471
3. P.T.W. van Hal, et al, (1994) J Immunol 153: 2718-2728.
4. H. Murray, et al, (1995) Leukemia & Lymphoma 17:501-508.
5. M Vigano, de Girolamo, et al. (Feb 2017) J Exp Orthopaedics 4: 8.