anti-CD1a R-PE Conjugate

The human CD1 genetic locus consists of five closely related genes (1).  Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, a subset of B cells, and on most professional antigen presenting cells (2).  CD1a+/CD11c+ dendritic cells are direct precursors of Langerhans cells in peripheral blood (4).  CD1 molecules have a specialized lipid antigen-presenting function (3)..

Isotype:  Murine IgG1kappa

Immunogen:  Human Jurkat tumor cells

Specificity:   Antibody CB-T6 recognizes the CD1a molecule of about 49 kd.   

References: 

1.  Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 33-37.

2.   Leukocyte Typing V (S.F. Schlossman, et al, eds.)  Oxford University Press, Oxford, (1995) p. 337-341. 

3.   E.M. Beckman, et al, (1994) Nature 372: 691-694. 

4.   T. Ito, et al, (1999) J Immunol  163: 1409-1419.

USD $275.00
In cart: 0
= $275.00
Catalog #:
145-050
Form:
R-PE
Size:
120 tests
Clone:
CB-T6
Applications:
FC

Application Key

FC
Flow Cytometry
WB
Western blot
EIA
Enzyme Immunoassay
IHC
Immunohistochemistry
ICC
Immunocytochemistry
FPS
Fixed paraffin section
PS
Paraffin section
IP
Immunoprecipitation
FX
Fixed cells or tissues

Applications indicated have been either tested in-house or reported. Products may be functional for applications not indicated.

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