Human CD235a (glycophorin A) is a sialoglycoprotein expressed early on the cell surface during erythropoiesis as pluripotent stem cells are recruited to differentiate into erythrocytes (1). CD235a (Glycophorin A) is a useful marker to study the developmental biology of hematopoietic progenitor cells (2,3).
Isotype: Murine IgM
Immunogen: Neuraminidase treated human erythrocytes
Specificity: Antibody A63-B/C2 reacts with an extracellular (peptide) domain of CD235a (glycophorin A)
1. J.G. Mark, et al, (1999) Blood 93: 4425-4435.
2. N. Debili, et al, (1996) Blood 88: 1284-1296.
3. B.M. Frey, et al, (1998) Blood 91: 2781-2792.