anti-CD80 (B7-1) R-PE Conjugate
Human CD80 (B7-1) is a costimulatory ligand for CD28 and CTLA-4 (1). CD80 is expressed on activated B cells (2).
Isotype: Murine IgG1
Immunogen: Human CD80 (B7-1) Ig Fusion Protein
Specificity: Antibody P1.H5.A1.A1 recognizes the CD80 molecule.
Functional Application: Antibody P1.H5.A1.A1 blocks binding of soluble CD152 Ig fusion protein to CD80.
References:
1. C.B. Thompson, (1995) Cell 81: 979-982.
2. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 682-684.