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PD-1 interaction is necessary for proper B cell memory development

By Paul Everson / February 11, 2025

“Is one lymphocyte’s brake another lymphocyte’s gas?” Thomas T Xu, Shiv Pillai. (Feb 7, 2025) Sci Immunol 10(104): eadw3656 doi: 10.1126/sciimmunol.adw365 PMID: 39919195

PD-1 (CD279) binding to its ligand PD-L1 (CD274) is down regulatory for T cell immune response in the context of cancer. However, studies are showing that this interaction is required for development of proper B cell memory.

Related Ancell Products

anti-human CD274 (PD-L1) products

anti-human CD279 (PD-1) products

Recombinant human CD279(PD-1)-muIg

Recombinant human CD274(PD-L1)-muIg

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