Oxidized Low Density Lipoprotein-Immune complexes linked to the Severity of Retinopathy in Type II Diabetes Patients

oxLDL-IC pathology was mediated by CD36 and CD64 receptors on retinal pericytes. 

“Immune complex formation in human diabetic retina enhances toxicity of oxidized LDL towards retinal capillary pericytes.” D Fu, T J Lyons, et al. (May, 2014) J Lipid Res 55: 860-869.  PMID: 24616481

Ancell reagents were used in this study to selectively block IC formation.

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