In mice, use of CD28 superagonist has been shown to increase the % of Treg cells, and protect from Rheumatoid Arthritis mediated bone destruction.Marlo M Zaiss, Jean-Pierre David, et al. (2010) J Immunol 184: 7238-7246. Ancell anti-CD28 antibody clone ANC28.1/5D10 has been characterized as a superagonist. This mAb has been found to be capable of stimulating […]