Maresin-1 is a Promising Candidate for Asthma Therapy

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The Macrophage Mediator, Maresin-1, is derived from the Omega-3 Fatty acid DHA. In a murine asthma model exogenously added Maresin-1 augmented T regulatory cells expansion and reduced lung inflammation with lower detectable levels of IL-5 and IL-13

 

“Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of Lung Inflammation”

Nandini Krishnamoorthy, Bruce D Levy, et al.(2015) Journal of Immunology 194: 863-867. PMID:25539814