Levels of the proinflammatory leptin correlated inversely with expansion of CD25+CD4+Foxp3+ T regulatory cells in a Systemic Lupus Erythematosus mouse model (NZB/W). This could lead to a leptin-based immunotherapy.”Cutting Edge: Fasting Induced Hypoleptinemia Expands Functional Regulatory T cells in Systemic Lupus Erythematosus”Yaoyang Liu, Yiyun Yu, Antonio La Cava, (2012) J Immunol 188: 2070-2073.
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