Emerging importance of Siglecs in assisting tumor evasion of immune surveillance

Siglecs and their ligands are expressed by many tumors, and can serve to down-regulate immune response.

REVIEW article: “The intriguing roles of Siglec family members in the tumor microenvironment” Kui-Ying Jiang, Ling Wang, et al. (2022) Biomarker Research 10: 22 PMID: 35418152

“Molecular Mechanism of Tumor Cell Immune Escape Mediated by CD24/Siglec-10” Shan-Shan Yin, Feng-Hou Gao (July 2020) Front. Immunol., 17 July 2020 | https://doi.org/10.3389/fimmu.2020.01324 PMID: 32765491

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