Cell Surface Metastatic Markers for Colon Cancer SW480/SW620 Model

SW480 is a primary Colon Epithelial Adenocarcinoma tumor line and SW620 is a metastasized variant of this derived from lymph node.  Differential analysis of surface markers may give insight into tumor metastatic potential and/or mechanisms.

 

“Multiplex Flow Cytometry Barcoding and Antibody Arrays Identify Surface Antigen Profiles of Primary and Metastatic Colon Cancer Cell Lines”

K Sukhedeo, J.N. Rich, et al. (2013) PLOSone 8(1): e53015.

 

Relevant Ancell Antibody Products

Antigens Upregulated after metastasis

CD10

CD4

CD43

CD24

 

Antigens Downregulated after metastasis

CD21

CD56

CD57

CD162

CD7

CD70

CD3

CD95

CD33

CD45RA

CD79b

CD100

CD271

CD6

CD75

CD54

CD55