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CD134(OX40) Signaling Mechanism Elucidated

By room34 / April 20, 2011

Engagement of CD134(OX40) by its Ligand (CD252) induces an intracellular signaling complex which  includes PKB, and PI3K, and requires TRAF2.

Takanori S, H Choi, M Croft. (2011) J Immunol 186(6):3547-3555.

 

Ancell Products:

Recombinant human CD134-muIg Fusion protein

Recombinant human CD252(OX40)-muCD8

Monoclonal anti-human CD134(OX40)

Monoclonal anti-human CD252(OX40L)

 

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