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CAR T cell efficacy improved by engineered expression of OX40(CD134)

By Paul Everson / December 5, 2025


OX40(CD134) expression on CAR T cell surface improves anti-tumor activity in a mouse model.


“OX40–heparan sulfate binding facilitates CAR T cell penetration into solid tumors in mice” Huihui Zhang, Xuanming Yang, et al. (18 June 2025) Science Translational Medicine 17(803):eadr2151. doi: 10.1126/scitranslmed.adr2151. Epub 2025 Jun 18. PMID: 405

Related Ancell Products

anti-human CD134(OX40) mAb

anti-human CD252(OX40L) mAb

Recombinant human CD134(OX40)

Recombinant human CD252(OX40L)

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