anti-CD137 (4-1BB) agonistic mAb alone improves tumor infiltration and anti-tumor response in mice.
Intratumoral Activation of 41BB Costimulatory Signals Enhances CD8 T Cell Expansion and Modulates Tumor-Infiltrating Myeloid Cells” Patrick Innamarato, Shari Pilon-Thomas, et al. (Oct 2020) J Immunol October 5, 2020, ji2000759; DOI: https://doi.org/10.4049/jimmunol.2000759.
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anti-human CD137 mAb clone 4B4-1