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anti-CD134(OX40) antibody Augments Teff function

By room34 / October 1, 2013

Agonistic humanized anti-CD134(OX40) antibodies improve T effector cell function by depleting T regulatory cells in vitro.  This approach has great potential for augmenting cancer therapy!

“Antibodies Targeting Human OX40 Expand Effector T Cells and Block Inducible and Natural Regulatory T Cell Function” K.S. Voo, Y.J. Liu, et al. (2013) J Immunol 191: 3641-3650. PMID: 24014877


Relevant Ancell Human Products:

anti-CD134(OX40)

anti-CD252(OX40L)

Recombinant CD134(OX40)

Recombinant CD252(OX40L) 

anti-CD357(GITR)

anti-CD278(ICOS)

anti-IFNgamma

anti-TNF alpha

anti-CD25

anti-CD4

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