CD38+ mast cells implicated in h pylori induced gastric cancerBy Paul Everson / February 2, 2026 H pylori infection leads to upregulation of COX2 and CD38 on mast cells, which suppress CD8+ T cell cytotoxicity through increased levels of PGE2 and adenosine. “Activated CD38+ mast cells promote gastric cancer progression by suppressing CD8+ T cell cytotoxic activity through adenosine metabolism” Jiabao Zhao, Xuehui Hong, et al. (2026 Jan 22) Cell Rep 45(2):116863. doi: 10.1016/j.celrep.2025.116863 PMID: 415 Related Ancell Products anti-human CD38 mAb products
