anti-IL-2 (clone N7-48A) R-PE Conjugate
Isotype: Mouse IgG2ak
Immunogen: Recombinant human IL-2
INFORMATION: The cytokine human interleukin-2 (IL-2) is a 15 kd protein expressed upon activation by peripheral TH1 cells, medullary thymocytes, and a subset of large granular lymphocytes. Secreted IL-2 stimulates proliferation and lymphokine production by T cells, B cells and NK cells. Clone N7-48A binds to intracellular IL-2 in flow cytometry.
References: 1. S.L. Swain (1991) Curr Opin Immunol 3-304-310. 2. A.K. Abbas, et al, (1996) Nature 383: 787-793. 3. A. Rebollo, et al, (1996) Advan Immunol 63: 127-196.